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The bioavailability of fentanyl in Matrifen® is fast and efficient

The fast bioavailability of fentanyl in the transdermal patch Matrifen® helps to relieve the severe chronic pain, such as cancer pain and low back pain.

The bioavailability of fentanyl in Matrifen® is fast and efficientMatrifen® has a fast bioavailability of fentanyl wich provides strong relief for all chronic pain. 

>> Information on the bioavailability of fentanyl

Matrifen® with its fast bioavailability of fentanyl provides pain relief to patients with prolonged or chronic severe pain. Following application of the patch to the skin, fentanyl is released into the systemic circulation by passive cutaneous diffusion.

Fentanyl has a high affinity for receptors located throughout the peripheral nervous system, the brain and the spinal cord, and binding to the receptors cause analgesia. 

About Nycomed
Nycomed is driving a new way of providing pharmaceutical products in Europe. Physicians are seeking new treatments that make a clear medical difference. But traditional pharmaceutical companies, with a single research department, are finding it harder to meet this need.

Nycomed, by contrast, can access the work of thousands of companies dedicated to research, and choose to make available the most innovative treatments.

Special features

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Mode of action video

An animation presenting the Matrifen® patch;
- Application
- Mode of action

Additional material

- Product details
- Pharmacokinetics
- Technical profile
Conversion tables for download 

- Oral morphine to Matrifen (100:1)
- Oral morphine to Matrifen (150:1)
- Potency table