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Learn more about opioid tolerance and Matrifen® the pain soother

Here you can read about opioid tolerance and the transdermal pain patch Matrifen® from Nycomed, that relieves severe chronic pain.

Information on opioid tolerance and Matrifen® Get more information on opioid tolerance and Matrifen® the patch, which provides relief for patients with severe chronic pain.

>> Information on opioid tolerance and Matrifen®

Opioid tolerance
The advanced matrix of Matrifen provides 72 hour pain relief equal to that of other matrix fentanyl patches however it is shown to have fewer side effects compared to morphine tablets and other oral formulations of opiod analgesics.

Matrifen has a lower drug load than other similar products, making it a more environmentally friendly medication, still it is a potent analgesic, approximately 50 to 100 times as potent as morphine.

About Nycomed
Nycomed is a pharmaceutical company dedicated to meeting needs in Europe. The company provides hospital products throughout the region and general practitioner and pharmacy medicines in selected markets.

New products are sourced through licensing agreements with research companies. Here Nycomed provides late-stage clinical development, registration and marketing. Nycomed employs about 3,500 people throughout Europe and Russia-CIS.

Special features

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Mode of action video

An animation presenting the Matrifen® patch;
- Application
- Mode of action

Additional material

- Product details
- Pharmacokinetics
- Technical profile
Conversion tables for download 

- Oral morphine to Matrifen (100:1)
- Oral morphine to Matrifen (150:1)
- Potency table